Know what’s inside:

Biomarker Services

GBA Group - Biomarker Services

High-performance (multi-array) ligand-binding assays

In vitro and in vivo studies: one sample – multiple readouts

The GBA Group supports the entire process of preclinical drug development: pharmacokinetics, pharmacodynamics, and toxicology, in order to predict the risk of harmful reactions and help you to choose the most suitable candidate for clinical trials.

Using leading-edge multi-array technologies we offer multiplex high-throughput detection, quantification and characterization of Biomarkers (cytokines, hormones, enzymes) and Biopharmaceuticals (e.g. monoclonal antibodies) in different biological matrices from pre-clinical (non-GLP/GLP) as well as clinical studies (GCLP).

These technologies require only small sample volumes and allow multiplex tests on a single sample with high sensitivity and reliability.

Dr. Daniel Da Costa

Your direct contact

Dr. Daniel Da Costa
BD Director Preclinical Services Europe

+49 173 889 42 77

BD@pharmacelsus.de

Pharmacokinetic / Toxicokinetic

  • Safety and Efficacy Determination
  • Liver and Kidney-tox

Biomarker Analysis

  • Metabolic
  • Immune
  • Cancer
  • Neuroscience
  • Allergic reaction

Immunogenicity Testing

  • Screening Assay

Immuneresponse

  • Innate
  • Adaptive
  • Anti-drug Antibodies

Matrixes

  • Ability to analyze a wide range of sample types e.g. cell culture supernatant, cell lysates/tissue homogenates, serum/plasma, whole Blood, sputum, urine, CSF, tumor extracts, tears, etc.

Technology

  • Luminex - xMAP (multianalyte profiling) Technology
  • Mesoscale MSD - Electrochemiluminescence based Multi-Array Technology

The experienced and highly committed GBA Group team offers a variety of different services the following in Areas:

GBA Group - In vitro ADME

In-Vitro ADME

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GBA Group - In vivo DMPK

In-Vivo DMPK

GBA Group - In vitro & in vivo Toxicology

In-Vitro & In-Vivo Toxicology

GBA Group - Biomarker Services

Biomarker Services

GBA Group - In vitro & in vivo Pharmacology

Safety Pharmacology

GBA Group - Preclinical Services

Nonclinical Services

Genotoxicology

Genotoxicology

General Toxicology

General Toxicology

Sensitisation

Sensitisation

Toxicology Additional Services

Toxicology: Additional Services

Corrosion and Irritation

Local Tolerance

Business Development

Contact us!

To learn more about us and what we can do for you please contact our Director Business Development.

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